Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands. National and Kapodistrian University of Athens School of Medicine, Athens University Hospital Attikon, Athens, Greece. Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, CT, USA. Heart Research Institute, Sydney, Australia. Department of Cardiology, Centro Hospitalar Universitário Lisboa Norte, CAML, CCUL@RISE, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal. Clinical Academic Group Cardiovascular, St George's University Hospital London, UK, Cardiology, San Raffaele Cassino, Italy. British Heart Foundation Centre of Research Excellence, School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK. CSL Vifor, Redwood City, CA, USA. CSL Vifor, HEOR, Glattbrugg, Switzerland.